| Date | PIX Time | Match | Round | Venue |
|---|
| 23-Jan-10 | | Preston North End 0 - 2 Chelsea | Round 4 | Deepdale |
| 23-Jan-10 | | Reading 1 - 0 Burnley | Round 4 | Madejski Stadium |
| 23-Jan-10 | | Accrington Stanley 1 - 3 Fulham | Round 4 | The Fraser Eagle Stadium |
| 23-Jan-10 | | Aston Villa 3 - 2 Brighton | Round 4 | Villa Park |
| 23-Jan-10 | | Bolton Wanderers 2 - 0 Sheffield United | Round 4 | Reebok Stadium |
| 23-Jan-10 | | Cardiff City 4 - 2 Leicester City | Round 4 | Cardiff City Stadium |
| 23-Jan-10 | | Derby County 1 - 0 Doncaster Rovers | Round 4 | Pride Park Stadium |
| 23-Jan-10 | | Everton 1 - 2 Birmingham | Round 4 | Goodison Park |
| 23-Jan-10 | | Notts County 2 - 2 Wigan Athletic | Round 4 | Meadow Lane |
| 23-Jan-10 | | Portsmouth 2 - 1 Sunderland | Round 4 | Fratton Park |
| 23-Jan-10 | | Southampton 2 - 1 Ipswich Town | Round 4 | St. Mary's Stadium |
| 23-Jan-10 | | West Bromwich Albion 4 - 2 Newcastle United | Round 4 | The Hawthorns |
| 23-Jan-10 | | Wolverhampton Wanderers 2 - 2 Crystal Palace | Round 4 | Molineux Stadium |
| 23-Jan-10 | | Tottenham Hotspur 2 - 2 Leeds United | Round 4 | White Hart Lane |
| 24-Jan-10 | | Stoke City 3 - 1 Arsenal | Round 4 | Britannia Stadium |
| 24-Jan-10 | | Scunthorpe United 2 - 4 Manchester City | Round 4 | Glanford Park |
| 2-Feb-10 | | Crystal Palace 3 - 1 Wolverhampton Wanderers | Round 4 | Selhurst Park |
| 2-Feb-10 | | Wigan Athletic 0 - 2 Notts County | Round 4 | The DW Stadium |
| 3-Feb-10 | | Leeds United 1 - 3 Tottenham Hotspur | Round 4 | Elland Road |
